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In a study in patients with PAH who were receiving stable dosages of sildenafil , administration of single doses of riociguat resulted in additive hemodynamic effects. In patients with severe renal impairment (creatinine clearance less than 30 mL/minute), the initial sildenafil dose for the treatment of ED should be decreased to 25 mg, since the drug’s effects may be prolonged and enhanced in such patients. Reported hearing loss was unilateral in most cases, and temporary in about one-third of the…

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Vardenafil is more selective than sildenafil and tadalafil to PDE5, which again means a lower dose is needed with potentially less side effects. Tadalafil is very specific for PDE5 and is also very specific for the enzyme PDE11. Unfortunately, we don’t know much about PDE11, which is found in the heart, in the pituitary gland in the brain and in the testicles. Pharmacokinetics, half-life, is how long the medication stay s in the blood. Sildenafil has a half-life of 4…

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Those tablets may be white, blue or green and may be round or oblong. Although the color and shape is different, there is virtually no difference in efficacy between sildenafil and brand name Viagra. Many prescription drugs treat ED like Stendra , Levitra , and Cialis , but Viagra is perhaps the most well-known and one of the most popular ED pills. TSU has earned a top 20 ranking for Historically Black Colleges and Universities according to U.S. Founded in…

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For older men on Medicare, he said the brand-name drugs can cost as much as $50 for one pill. Dr. Warren Bromberg is chief of urology at Northern Westchester Hospital in Mount Kisco, N.Y. He agreed that cost has been an issue with these drugs. VIAGRA does not protect against sexually transmitted diseases, including HIV. Check your pills to be sure they’re brand-name VIAGRA—not the generic. If you think your brand-name prescription has been filled with a generic, talk to…

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